I. Introduction to NR
Nicotinamide Riboside (NR) is a pyridine nucleoside, a vitamin B3 derivative formed by combining the sugar molecule ribose and the vitamin B3 component nicotinamide. This substance is not only naturally present in foods such as meat, fish, and cereals, but can also be taken as a supplement. NR acts as a precursor of nicotinamide adenine dinucleotide (NAD+) in the body through two-step and three-step pathways, which is an important coenzyme involved in a variety of cellular metabolic processes, including energy production, DNA repair, and cell proliferation.
As we age, the amount of NAD+ in the human body gradually decreases, and NR supplementation can increase NAD+ levels, which is expected to delay the occurrence of cell aging and related diseases. Therefore, as a potential dietary supplement, NR has attracted the attention of researchers for its application prospects in promoting healthy aging and improving cellular metabolic function. Through these pathways, NR can not only supplement vitamin B3, but also indirectly enhance the level of NAD+ in cells, thereby supporting cell health and function.
II. Introduction to the Efficacy of NR
1. Antioxidation and anti-aging
NR has a significant antioxidant effect, which can remove free radicals in the body, reduce oxidative stress, and protect cells from damage. Studies have found that supplementing NR can increase the level of nicotinamide adenine dinucleotide (NAD+) in the body, thereby activating the longevity protein Sirtuins and delaying the cell aging process.
2. Improve cardiovascular function
NR has a protective effect on the cardiovascular system. Studies have shown that supplementing NR can lower blood pressure, improve endothelial function, and reduce the occurrence of atherosclerosis. In addition, NR can also improve the energy metabolism of myocardial cells and enhance heart function.
3. Improve immunity
NR can enhance the body's immunity. Studies have found that supplementing NR can increase the level of NAD+ in the body, thereby enhancing the function of T lymphocytes and improving the body's defense against pathogenic microorganisms.
4. Protect the liver
NR has a protective effect on the liver. Studies have shown that NR can reduce liver fat content, improve liver inflammatory response, and prevent the occurrence of non-alcoholic fatty liver disease. In addition, NR can also increase the activity of liver detoxification enzymes and enhance the liver's detoxification ability.
5. Improve diabetic symptoms
NR has a certain auxiliary therapeutic effect on diabetic patients. Studies have found that supplementing NR can improve insulin sensitivity, lower blood sugar levels, and improve the symptoms of diabetic patients.
6. Improve exercise capacity
NR can improve exercise capacity. Studies have shown that supplementing NR can increase the level of NAD+ in muscle cells, improve muscle energy metabolism, reduce exercise fatigue, and enhance exercise endurance.
III. Summary
Nicotinamide riboside chloride (NR) is a new dietary supplement with multiple functions such as anti-oxidation, anti-aging, improving cardiovascular function, improving immunity, protecting the liver, improving diabetes symptoms, and improving exercise ability. Appropriate supplementation of NR helps maintain good health and improve the quality of life. However, it should be noted that dietary supplements are not omnipotent, and a reasonable diet, regular work and rest, and moderate exercise are still the key to maintaining health. Before supplementing NR, please consult a professional doctor or nutritionist for advice.