Nicotinamide Riboside Chloride, Nicotinamide Riboside
Nicotinamide Riboside Chloride is a newly appreciated form of Vitamin B3, with unique properties, it is a formal precursor of NAD+. Nicotinamide riboside (NR), first described in 1944 as a growth factor (Factor V) for Haemophilus influenza, and in 1951, NR, first investigated as a metabolic fate in mammalian tissues.
Synonym
Nicotinamideribosidechloride; NicotinamideB-DRibosideChloride(WX900111); NicotinamideRiboside.Cl; Nicotimideribosidechloride; Pyridinium,3-(aminocarbonyl)-1-β-D-ribofuranosyl-,chloride(1: 1); 3-carbamoyChemicalbookl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-iumchloride; 3-Carbamoyl-1-(β-D-ribofuranosyl)pyridiniumchloride; 3-Carbamoyl-1-beta-D-ribofuranosylpyridiniumchloride
● CAS No.: 23111-00-4
● EC No.: 200-184-4
● MF: C11H15N2O5.Cl
● MW: 290.7
Parameters of Nicotinamide Riboside Chloride, Nicotinamide Riboside
|
Item |
Standard |
Results |
|
Appearance |
White Powder |
Conforms |
|
Identification |
H-NMR |
Conforms |
|
Loss On Drying |
≤2.0% |
0.78% |
|
Residue On Ignition |
≤0.5% |
0.15% |
|
Heavy Metals |
≤20ppm |
< 20 ppm |
|
Lead (Pb) |
≤1.5ppm |
Not Detected |
|
Cadmium (Cd) |
≤0.18ppm |
Not Detected |
|
Mercury (Hg) |
≤0.002ppm |
Not Detected |
|
Arsenic (As) |
≤0.01ppm |
Not Detected |
|
Coliforms |
100cfu/g Max |
Conforms |
|
E.Coli |
Negative/10g |
Conforms |
|
Salmonella |
Negative/25g |
Conforms |
|
Staphylococcus |
Negative/10g |
Conforms |
|
Total Plate Count |
100cfu/g Max |
Conforms |
|
Yeast And Molds |
100cfu/g Max |
Conforms |
|
Methanol |
≤10ppm |
Conforms |
|
Purity By HPLC |
≥98% |
99.5% |
● Packing: 100g/bag; 500g/bag; 1kg/bag; 25kg/drum
● Recommended storage method: Store in a cool, dry and ventilated place.
● Recommended storage temperature: 2-8°C
● Product usage: Dietary Supplements
Benefits of Nicotinamide Riboside Chloride
Help energy generation
In animals, Nicotinamide Riboside Chloride supplementation reduced NAD consumption, which improved mitochondrial function, rapidly restored muscle mass, and conserve strength NAD levels and exercise volume in older mice.
Improve cognitive function
NR preserves the nerve cells in the brain by activating the SIRT3 and Supplementation stimulates the NAD pathways and helps prevent degeneration in mind.
Protect the liver
Taken NR Orally increases NAD in the body, which helps protect the liver. Furthermore, NR could extend longevity, Increases metabolism, supports the fight against cancer, reduce diabetic symptoms, increases metabolism, may help with weight loss.
Prevent hearing loss
By activating the SIRT3 pathway, a UNC study found it helped protect rodents against noise-induced hearing loss.
Why Nicotinamide Riboside Chloride (NR) Designate As An Authentic Nad+ Precursor Vitamin Invertebrates?
● Haemophilus influenza is strictly dependent on NR, NMN, or NAD+ for growth in the host bloodstream.
● Milk is a source of NR.
● NR protects murine DRG neurons.
● Exogenously added NR and derivatives increase NAD+ accumulation in human cell lines.
● Candida glabrata utilizes NR during disseminated infection.