Product Brief Introduction
Product name: Domperidone
CAS：57808-66-9
MF: C22H24ClN5O2
MW: 425.911
Product Specification
|
Item |
Specification |
|
Appearance |
White or off-white powder |
|
Identification |
A.IR: The infrared absorption spectrum of the sample complies with the reference standard. |
|
|
B.TLC: The principal spot in the chromatogram obtained with the test solution is similar in position and size to the principal spot in the chromatogram obtained with reference solution(a). |
|
|
C.Test for non-nitrogen substituted barbiturates: a violet blue color and precipitate should appear. |
|
Solubility |
Practically insoluble in water, soluble in Dimethyl formamide and slightly soluble in ethanol and methanol. |
|
Appearance of Solution |
The solution is clear and not more intensely coloured than reference solution Y6. |
|
Melting Point |
244.0℃-248.0℃ |
|
Loss on Drying (105℃) |
≤ 0.5% |
|
Sulfated Ash |
≤ 0.1% |
|
Related Substances (HPLC) |
Impurity A ≤ 0.25% |
|
Impurity B ≤ 0.25% |
|
|
Impurity C ≤ 0.25% |
|
|
Impurity D ≤ 0.25% |
|
|
Impurity E ≤ 0.25% |
|
|
Impurity F ≤ 0.25% |
|
|
Total impurities ≤ 0.5% |
|
|
Heavy Metals |
≤ 20ppm |
|
Assay (on dries basis) |
99.0%-101.0% |
