Product Brief Introduction
Product name: Midodrine Hydrochloride
CAS：3092-17-9
MF: C12H19ClN2O4
MW: 290.743
Product Specification
|
Item |
Specification |
|
Appearance |
White crystal or crystalline powder |
|
Odor |
Odorless |
|
Taste |
Taste bitter |
|
Solubility |
This product is soluble in water, slightly soluble in methanol, almost insoluble in acetone or ethyl acetate, and insoluble in ethyl acetate. |
|
Absorption Coefficient |
The absorption coefficient (E1%1CM) of this product should be 110~120 |
|
Identification |
The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay. |
|
IR: The infrared absorption spectrum of the sample complies with the reference standard. |
|
|
Chemical reactions: It gives positive reaction |
|
|
Melting Point |
197.0℃-201.0℃ |
|
PH |
4.5~5.5 |
|
Loss on Drying |
≤ 0.5% |
|
Residue on Ignition |
≤ 0.1% |
|
Related Substances |
Impurity A ≤ 0.2% |
|
|
Single impurity ≤ 0.2% |
|
|
Total impurities ≤ 0.5% |
|
Glycine |
If the test solution shows a spot corresponding to glycine, its color should not be darker than the main spot of the reference solution.(0.4%) |
|
Residual Solvents |
n-Heptane ≤ 5000ppm |
|
Isopropyl Ether ≤ 5000ppm |
|
|
Methanol ≤ 3000ppm |
|
|
Ethanol ≤ 5000ppm |
|
|
Acetonitrile ≤ 410ppm |
|
|
Toluene ≤ 890ppm |
|
|
Dichloromethane ≤ 600ppm |
|
|
Chloroform ≤ 60ppm |
|
|
Heavy Metals |
≤ 20ppm |
|
Total Plate Count |
≤ 1000cfu/g |
|
Yeasts&Molds |
≤ 100cfu/g |
|
E.Coli |
Negative/g |
|
Assay (on dried basis) |
≥ 98.5% |
