Ibuprofen;CAS 15687-27-1

Item

Specification

Appearance

White crystalline powder

Identification

IR: The Infrared spectrum of sample should be concordant with that of standard.

B.UV: The spectrum of sample does not differ from that of the standard by more than 3.0%

C.HPLC: The retention time corresponds to that of the standard

Solubility

Practically insoluble in water, very soluble in alcohol, in methanol, in acetone and in chloroform, slightly soluble in ethyl acetate.

Moisture

≤1.0%

Residue on ignition

≤0.5%

Bulk Density

0.2-0.5 g/ml

Tapped Density

0.4-0.7 g/ml

Median Particle Size

30-60 μm

Chromatographic Purity

2-[3-(2-methylpropyl)phenyl]propanoic acid ≤0.15%

2-(4-ethylphenyl )propanoic acid ≤0.15%

2-(4-methylphenyl)propanoic acid ≤0.15%

2-(4-propylphenyl)propanoic acid ≤0.15%

2-(4-butylphenyl)propanoic acid ≤0.1%

Any unspecified impurity ≤0.05%

Total impurities ≤0.6%

Related Compound C

(4-Isobutylacetophenone)

≤0.1%

Residual Solvents

Methanol ≤3000ppm

Toluene ≤890ppm

Petroleum ether ≤250ppm

Assay (on dried basis)

97.0%-103.0%