Product Brief Introduction
Product name:Betamethasone Base
CAS:378-44-9
MF:C22H29FO5
MW:392.461
Product Specification
|
Item |
Specification |
|
Appearance |
White or off-white crystalline powder |
| Identification |
Complies with the standard |
|
Complies with the standard |
|
|
Solubility |
Practically insoluble in water, sparingly soluble in anhydrous ethanol, very slightly soluble in methylene chloride. |
|
Specfic optical rotation |
+118.0°- +126.0° |
|
Particle size |
100% ≤ 100 μm |
|
Loss on drying |
≤0.5% |
|
Related Substances
|
Impurity A ≤1.0% |
|
Impurity B ≤1.0% |
|
|
Impurity C ≤1.0% |
|
|
Impurity D ≤1.0% |
|
|
Impurity E ≤1.0% |
|
|
Impurity F ≤1.0% |
|
|
Impurity G ≤1.0% |
|
|
Impurity H ≤1.0% |
|
|
Impurity I ≤1.0% |
|
|
Impurity J ≤1.0% |
|
|
Impurity 0.5%-1.0% |
|
|
Total impurities |
≤2.0% |
|
Residual Solvents
|
Ethyl acetate ≤5000ppm |
|
Acetone ≤5000ppm |
|
|
Methanol ≤3000ppm |
|
|
DMF ≤800ppm |
|
|
Dichloromethane ≤200ppm |
|
|
Chloroform ≤60ppm |
|
|
Assay (UV, On dried basis) |
97.0%-103.0% |
