Apigenin 7-Glucoside; CAS 578-74-5

Appearance

Slight-yellowish powder

Identification

A. Infrared absorption spectrophotometry: Comparison: Apigetrin RS.

B: Examine the chromatograms obtained in the assay by HPLC.

Solubility

Practically insoluble in water, free soluble in dimethyl sulfoxide, sparingly soluble in ethanol (96%), soluble in dilute solutions of alkali hydroxides.

Loss on Drying

≤ 5.0%

Sulfated Ash

≤ 0.2%

Loose Bulk Density

0.2~0.4g/ml

Tapped Density

0.4~0.6g/ml

Related Substances

Impurity A: Rhoifolin ≤ 1.0%

Impurity B: Apigenin ≤ 1.0%

Any other impurity ≤ 2.0%

Total impurities ≤ 5.0%

Heavy Metals (as Pb)

≤ 20ppm

Lead

≤ 0.5ppm

Arsenic

≤ 1.5ppm

Cadmium

≤ 0.5ppm

Mercury

≤ 0.1ppm

Residual Solvents

Ethanol ≤ 5000ppm

Methanol ≤ 3000ppm

Pyridine ≤ 200ppm

Total Aerobic Microbial Count

≤ 1000cfu/g

Yeasts & Molds

≤ 100cfu/g

E.Coli

Negative in lg

Assay (HPLC)

≥ 95.0%