Product Brief Introduction
Product name: Flurbiprofen
CAS：5104-49-4
MF: C15H13FO2
MW: 244.261
Product Specification
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Item |
Specification |
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Appearance |
White or off-white crystalline powder |
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Identification |
Take about 1 ml of saturated sulfuric acid solution of chromium trichloride, put it in a small test tube, rotate the test tube, the solution should be evenly applied to the tube wall, add about 2 mg of this product, heat slightly, rotate the test tube, the solution should no longer be evenly applied to the tube wall, and oil-like stains will exist on the tube wall. |
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IR: The infrared absorption spectrum of the sample complies with the reference standard. |
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UV: The maximum absorption is at a wavelength of 247±2nm |
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Solubility |
Freely soluble in methanol, ethanol (95%), acetone or ether, soluble in acetonitrile, practically insoluble in water |
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Specific Rotation |
-0.1°~ +0.1° |
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Melting Point |
114.0℃~117.0℃ |
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Loss on Drying |
≤ 0.5% |
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Residue on Ignition |
≤ 0.1% |
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Sulfate (SO42-) |
≤ 0.1% |
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Chloride (Cl-) |
≤ 0.015% |
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Nitrite Compounds |
≤ 5ppm |
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Related Substances |
Impurity A ≤ 0.5% |
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Impurity B ≤ 0.2% |
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Impurity C ≤ 0.2% |
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Impurity D ≤ 0.2% |
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Impurity E ≤ 0.1% |
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Impurity F ≤ 0.1% |
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Impurity G ≤ 0.1% |
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Other single impurity ≤ 0.1% |
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Total impurities ≤ 0.7% |
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Heavy Metals |
≤ 10ppm |
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Residual Solvents 1 |
Methanol≤ 0.3% |
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Ethanol≤ 0.5% |
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Isopropyl alcohol≤ 0.5% |
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Dichloromethane≤ 0.06% |
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n-Hexane≤ 0.029% |
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Ethyl acetate≤ 0.5% |
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Isobutanol≤ 0.5% |
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Toluene≤ 0.089% |
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N,N-Dimethylformamide≤ 0.088% |
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Residual Solvents 2 |
Benzene≤ 0.0002% |
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Thiophene≤ 0.0005% |
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Residual Solvents 3 |
Acetic acid≤ 0.5% |
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Trichloroacetic acid≤ 0.1% |
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Total Plate Count |
≤ 1000cfu/g |
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Yeasts&Molds |
≤ 100cfu/g |
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Staphylococcus Aureus |
Negative/g |
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Pseudomonas Aeruginosa |
Negative/g |
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Assay (on dried basis, as C15H13FO2) |
99.0%-100.5% |
