GIHI CHEMICALS CO., LIMITED. Since 2010
Afoxolaner

Parameters of Afoxolaner

Item

Specification

Results

Appearance

White To Off-white Crystalline Powder

Complies

Identification

HPLC: HPLC Retention Time Confirms To Standard

Complies

Melting Point

148-155℃

148-150℃

Water

≤0.1%

0.07%

Residue Solvents

Dichloromethane≤600ppm

N.D.

Isopropyl Acetate≤5000ppm

N.D.

Isopropanol≤890ppm

2ppm

N, N-Dimethylformamide≤880ppm

N.D.

Methanol≤3000ppm

N.D.

Tetrahydrofuran≤720ppm

N.D.

Triethylamine≤5000ppm

N.D.

Residue On Ignition

≤0.1%

0.02%

Related Substances

Impurity D≤0.15%

N.D.

Impurity F≤0.15%

0.08%

Individual Unknown Impurity≤0.10%

0.06%

Total Impurities≤1.00%

0.38%

Assay(Anhydrous Substance)

98.0%~102.0%

99.10%


Packing:

100g/bag; 500g/bag; 1kg/bag

Recommended storage method:

Store in a cool, dry and ventilated place.

Recommended storage temperature:

2 - 8 °C

Product usage:

Pharmaceutical intermediates

Benefits of Afoxolaner

Treat and control flea and tick infestations in dogs.

When fleas or ticks bite the dog, they are exposed to the drug and killed during their blood meal.

The treatment of sarcoptic mange or demodectic mange.

When afoxolaner is prescribed for the treatment of mange, it is referred to as 'extra label' or 'off label' use. 

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